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B12 Nootropic and Brain Supplement Benefits


Vitamin B12: A Powerful Nootropic for Brain Health and Clarity

Vitamin B12 (Methylcobalamin) is a crucial nutrient for our body, and it plays a vital role in maintaining our brain health and cognitive functions. It is involved in numerous processes such as DNA synthesis, red blood cell formation, and proper functioning of the nervous system. Many people are unaware of the B12 benefits and its importance as a nootropic.

B12 Deficiency: Symptoms and Causes

A vitamin B12 deficiency can lead to various health problems, including fatigue, weakness, memory loss, and even neurological symptoms. Some common B12 deficiency symptoms include:

  • Fatigue and weakness
  • Memory problems and confusion
  • Tingling and numbness in hands and feet
  • Difficulty walking
  • Mood swings and depression

Several factors can contribute to a B12 deficiency, such as poor diet, digestive issues, and certain medications. Older adults and vegans are at a higher risk of developing a deficiency due to their limited dietary sources of B12.

Foods Rich in B12

A well-balanced diet can help ensure you get enough vitamin B12. Some excellent B12 foods include:

  • Meat, such as beef and liver
  • Fish, like salmon and tuna
  • Poultry, such as chicken and turkey
  • Dairy products, like milk, yogurt, and cheese
  • Eggs
  • Fortified cereals and plant-based milk alternatives

However, it can be challenging to obtain adequate levels of B12 through diet alone, especially for those with dietary restrictions or absorption issues. In such cases, B12 supplements or B12 shots can help maintain healthy B12 levels.

B12 as a Nootropic: Benefits for Cognitive Function

Vitamin B12 offers several nootropic benefits that can improve brain health, memory, and mental clarity:

  1. Supports Neurotransmitter Production: B12 is involved in the synthesis of neurotransmitters, such as dopamine and serotonin, which play a crucial role in mood regulation, memory, and learning.

  2. Enhances Memory Function: B12 helps maintain healthy nerve cells and supports the formation of myelin sheaths, which protect nerve fibers and enable efficient transmission of nerve impulses. This process is essential for optimal memory function.

  3. Boosts Energy Levels: B12 plays a vital role in converting carbohydrates into glucose, which the body uses for energy. By supporting energy production, B12 can help improve mental clarity and focus.

  4. Promotes Brain Health: B12 has been shown to have neuroprotective properties, and it can help reduce inflammation and oxidative stress in the brain.

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Nootropics Are Substances That Can Enhance Memory, Brain Health, Focus, Mood and Other Cognitive Processes, While Safely Supporting and Protecting Different Areas of the Brain. †

B12 Nootropic Statistics and Medical Research

Vitamin B12 plays a vital role in various functions of the human body, including cognitive performance and overall brain health. Several medical research studies have provided fascinating insights into the impact of B12 on our cognitive functions. Let’s take a closer look at some key statistics and findings:

  1. Prevalence of B12 Deficiency: According to the National Institutes of Health (NIH), B12 deficiency affects between 1.5% to 15% of the general population. The elderly, vegans, and vegetarians are at a higher risk of developing a deficiency due to their limited intake of animal products containing B12.

  2. Cognitive Function and B12 Deficiency: A study published in the American Journal of Clinical Nutrition found that B12 deficiency is associated with cognitive decline, particularly in older adults. The research showed that adequate B12 intake is crucial for maintaining optimal brain health.

  3. B12 and Memory: A 2012 study demonstrated that low serum B12 levels were linked to poor memory performance. Ensuring optimal B12 levels can support memory functions and help prevent memory decline.

  4. B12 Supplementation and Cognitive Improvement: A 2013 meta-analysis found that B12 supplementation could lead to modest improvements in cognitive performance, particularly in individuals with pre-existing B12 deficiencies or age-related cognitive decline.


These medical research findings underscore the importance of maintaining optimal vitamin B12 levels for cognitive health and overall brain function. Iso Brain combines vitamin B12 with other potent nootropic ingredients to provide a powerful formula that supports memory, focus, and mental clarity. Experience the cognitive benefits of Iso Brain and elevate your mental performance to new heights.

vitamin b12

Iso Brain: A Comprehensive Nootropic Formula

Iso Brain is a powerful nootropic supplement that combines the cognitive benefits of vitamin B12 with other potent ingredients to support overall brain health and cognitive function. The Iso Brain formula includes:

  1. Vitamin D3 (Cholecalciferol)]: Supports brain health and mood regulation by maintaining healthy levels of serotonin and dopamine.
  1. Vitamin B3 (Niacin): Promotes proper brain function by aiding in the production of neurotransmitters and energy metabolism.

  2. Vitamin B6 (P5P) (Pyridoxal 5 Phosphate): Helps maintain optimal neurotransmitter balance, supporting mood and cognitive function.

  3. Acetyl L-Carnitine (ALCAR): Enhances mitochondrial function in brain cells, providing more energy for cognitive processes.

  4. Lion’s Mane (Hericium Erinaceus): Promotes nerve growth factor (NGF) production, supporting neuron growth and regeneration.

  5. Cognizin® (Citicoline): Supports brain health by providing essential nutrients for the synthesis of phosphatidylcholine, a key component of cell membranes.

  6. N-Acetyl L-Tyrosine (NALT): Increases the availability of neurotransmitters, improving focus and cognitive flexibility under stress.

  7. Rhodiola Rosea Extract (5% Rosavins): Enhances the body’s resistance to stress and promotes cognitive function.

  8. N-Acetyl Cysteine (NAC): Supports antioxidant defense and helps maintain a healthy balance of neurotransmitters.

  9. Bacopa Monniera Extract (50% Bacosaponins): Improves memory and learning by modulating the activity of key neurotransmitters.

  10. Tumeric Extract (95% Curcuminoids): Provides potent antioxidant and anti-inflammatory properties that support brain health.

  11. Phosphatidylserine (From Sunflower): Helps maintain optimal brain cell function and supports memory and learning.

  12. Dimethylaminoethanol (DMAE Bitartrate): Improves focus and mental clarity by increasing acetylcholine production.

  13. Coenzyme Q10 (CoQ10): Provides antioxidant protection for brain cells and supports energy production.

Clinical Research on Iso Brain Ingredients

For those interested in the clinical research behind the ingredients in Iso Brain, we invite you to visit our Clinical Research page. This comprehensive resource provides detailed information on the scientific evidence supporting the effectiveness and safety of the ingredients found in Iso Brain.

Iso Brain: Safe and Effective Cognitive Support

Iso Brain is designed to be safe when used as directed, providing a powerful blend of nootropic ingredients to support optimal brain health, memory, and mental clarity. By choosing Iso Brain, you can trust that you are investing in a high-quality nootropic supplement backed by science.

In Iso Brain, vitamin B12 is an essential nutrient that offers numerous nootropic benefits, making it a crucial component in any brain health supplement. Iso Brain combines the power of vitamin B12 with other carefully selected ingredients to create a comprehensive nootropic formula that supports cognitive function, memory, and overall brain health.

Don’t miss out on the opportunity to experience the benefits of Iso Brain for yourself. Try Iso Brain today and unlock your full cognitive potential!

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Synergy of Iso Brain’s Ingredients

While vitamin B12 is an essential component for cognitive health, Iso Brain’s advanced formula goes above and beyond, combining a range of powerful nootropic ingredients to support and enhance overall brain function. Let’s explore some of the other key ingredients in Iso Brain and their unique benefits:

  1. Vitamin D3 (Cholecalciferol): Often referred to as the “sunshine vitamin,” vitamin D3 is crucial for maintaining optimal brain health. It has been shown to promote neuron growth, enhance cognitive function, and support a healthy mood.

  2. Vitamin B3 (Niacin): Niacin plays a vital role in energy production and brain function. It helps improve blood flow to the brain, supports neurotransmitter production, and promotes overall cognitive health.

  3. Vitamin B6 (P5P) (Pyridoxal 5 Phosphate): This active form of vitamin B6 is involved in over 100 enzyme reactions in the body, primarily related to the metabolism of amino acids and neurotransmitters. It supports cognitive function, mood regulation, and memory.

  4. Acetyl L-Carnitine (ALCAR): ALCAR is an amino acid that boosts mitochondrial energy production, promotes neuroprotection, and enhances cognitive performance.

  5. Lion’s Mane (Hericium Erinaceus): A powerful medicinal mushroom, Lion’s Mane has been shown to stimulate nerve growth factor (NGF) production, supporting neuron health and cognitive function.

  6. Cognizin® (Citicoline): Cognizin® is a patented form of citicoline, a natural compound that supports brain health, improves focus, and enhances memory.

  7. N-Acetyl L-Tyrosine (NALT): NALT is an amino acid that serves as a precursor to essential neurotransmitters, including dopamine, norepinephrine, and epinephrine. It enhances cognitive function, mood, and stress resilience.

  8. Rhodiola Rosea Extract (5% Rosavins): This adaptogenic herb is known for its ability to combat stress, reduce fatigue, and promote mental clarity and focus.

  9. N-Acetyl Cysteine (NAC): NAC is an antioxidant that supports glutathione production, promoting detoxification and protecting brain cells from oxidative stress.

  10. Bacopa Monniera Extract (50% Bacosaponins): Bacopa is a traditional Ayurvedic herb that has been shown to improve memory, learning, and cognitive function.

  11. Turmeric Extract (95% Curcuminoids): Turmeric contains potent anti-inflammatory and antioxidant compounds called curcuminoids, which support brain health and cognitive function.

  12. Phosphatidylserine (From Sunflower): Phosphatidylserine is a phospholipid that plays a critical role in maintaining cell membrane integrity, particularly in brain cells. It has been shown to improve cognitive function, memory, and focus.
  1. Dimethylaminoethanol (DMAE Bitartrate): DMAE is a natural compound that increases the production of acetylcholine, a neurotransmitter involved in learning and memory. It supports mental focus, alertness, and overall cognitive health.

  2. Coenzyme Q10 (CoQ10): CoQ10 is a powerful antioxidant that plays a vital role in cellular energy production. It supports brain health, improves cognitive function, and protects against age-related cognitive decline.

Together, these ingredients in Iso Brain work synergistically to deliver a comprehensive nootropic supplement designed to optimize cognitive performance, support brain health, and promote overall well-being. For more in-depth information on the clinical research behind each ingredient in Iso Brain, be sure to visit our Clinical Research page.

Iso Brain is safe to use as directed, and its unique blend of scientifically-backed ingredients makes it a powerful ally in supporting and enhancing cognitive function. Experience the benefits of Iso Brain for yourself, and don’t forget to explore our online shop to order your supply today!


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"ISO brain 100% transparency promise"

We are transparent like our bottles, showing you an itemized breakdown of the exact amounts of our ingredients. You will not open a clear ISO BRAIN bottle to find it half full like a bag of chips and you will know exactly how much you are taking of each ingredient.

Supplement Facts

Serving Size 2 Capsules
Servings Per Container 30

† Percent Daily Value not established

Other Ingredients: Gelatin Capsule (Sodium Lauryl sulfate, Glycerin, Brilliant Blue FCF, FD & C Red No. 40, Titanium Dyoxide), Magnesium Stearate, Silicon Dioxide, Microcrystalline Cellulose, Maltrodextrin.

Coginizin® is a registered trademark of KYOWA HAKKO BIO CO, LTD.

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Discover the incredible benefits of Iso Brain for yourself, and take advantage of our 90-day money-back guarantee. We’re confident that you’ll be amazed by the improvements in cognitive performance, focus, and overall well-being that Iso Brain can offer. If for any reason you’re not completely satisfied with your purchase, just let us know within 90 days, and we’ll refund your money—no questions asked. Don’t miss out on this opportunity to unlock your brain’s full potential. Visit our online shop and order your supply of Iso Brain today!


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Made In The USA
Itemized Ingredient Amounts
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15 Premium Ingredients

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Vitamin B6 (P5P)

(Pyridoxal 5 Phosphate)5

Pyridoxal-5-Phosphate, or P5P as it is commonly known, is a more expensive and active form of vitamin B6. P5P is a required coenzyme for the biosynthesis of several neurotransmitters, including GABA, dopamine, norepinephrine, and serotonin. Some studies show P5P increasing mood, memory, performance and mental effort.†

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(ALCAR) 333mg

An amino acid that is naturally produced in the body which helps produce energy and can help increase energy production in the mitochondria. This acetylated version of carnitine is able to cross the blood-brain barrier. Its primary effect is on the production of acetylcholine which is one of the main neurotransmitters involved in memory, learning, computation, analysis and many other cognitive processes.†

LionsMane2 compact


(Hericium Erinaceus) 216mg

Hericium Erinaceus (also called Lion’s Mane) is an edible and medicinal mushroom. Lion’s Mane can induce Nerve Growth Factor synthesis in nerve cells which is essential for the maintenance of the basal forebrain cholinergic system. A double-blind placebo-controlled clinical trial study showed increased cognitive function scores for people who took Lion’s Mane vs a placebo group. †

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Bacopa Monniera Extract

(50% Bacosaponins)94mg

Created from the Brahmi plant which is native to the wetlands of India and has been a consistent part of traditional medicine for centuries. A 2013 study demonstrated that Bacopa Monniera extract has a potential to improve cognitive performance, particularly speed of attention by reducing choice reaction time.†

tumeric compact


(95% Curcuminoids) 87mg

Curcumin is a natural phenolic component of yellow curry spice, which is used in some cultures for the treatment of diseases associated with oxidative stress and inflammation. Recent studies show that curcumin also possesses neuroprotective and cognitive-enhancing properties.†

Phosphatidylserine 01 medium


(From Soy) 74mg

Phosphatidylserine is a phospholipid and is a component of the cell membrane. It plays a key role in cell cycle signaling, specifically in relationship to apoptosis. In a recent Japenese study, with oral administration of Soy-PS for 6 months improved memory function, especially delayed recall, in the elderly with memory complaints. †

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An amino acid considered a “building block” of protein. in some cases L-Tyrosine is also used to treat depression, anxiety, ADHD, cognitive disorders and treat chronic fatigue syndrome.†

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(5% Rosavins)106mg

Rhodiola rosea is a perennial flowering plant in the family Crassulaceae. In some clinical trials Rhodiola Rosea has been found to show anti fatiguing benefits for brain function.†

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N-acetyl cysteine (sometimes refered to as NAC) comes from the amino acid L-cysteine, that has been known as a strong antioxidant and one of the few supplements to help combat hangover symptoms from Alcohol.†

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(DMAE Bitartrate) 58mg

DMAE is a precursor to acetylcholine, which is one of the main memory-forming neurotransmitters in your brain. Higher acetylcholine levels have been linked with better performance on some memory tests.† As a nootropic, it is closely related to choline but due to a slightly different chemical structure it crosses the blood-brain barrier differently.†

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(Cholecalciferol) 400 IU

Vitamin D acts an immune system modulator and can be produced by the body using sunlight. present findings signify the crucial role of Vitamin D on the basic synaptic transmission and synaptic plasticity.† Due to weather changes, deficiency is common during the winter months. A recent study suggests that Vitamin D(3) supplementation during the winter may reduce the incidence of flu by 40%†

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(CoQ10) 50mg

COQ10: Co-Enzyme Q10 is a compound present in mitochondria of every cell in the body. the results show that lower COQ10 plays a role in the pathophysiology of depression and in particular in TRD and CFS accompanying depression.† COQ10 supplementation also has been known to promote slower brain deterioration, as seen in a study published in the 2002 “archives of neurology.” †

Cognizin 1



Cognizin®​ delivers a patented form of citicoline. Citicoline is a brain health ingredient that provides support for attention, focus and recall. Clinical studies have shown Cognizin to help improve attention, focus, motor speed and increase brain activity. †
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MethylCobalamin is more Bio-Available and expensive form of B12. The vitamin plays a key role in the normal functioning of the brain and nervous system.†

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(Niacin) 20mg

Also known as Niacin. this vitamin is known as a key Co-Enzyme in the production of cellular energy. Data from research suggests Vitamin B3 may be beneficial in preserving and enhancing neuroconitive function.†

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