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Rhodiola Rosea Nootropic Research in Iso Brain 2023


Rhodiola Rosea: A Powerful Nootropic for Peak Cognitive Performance

Rhodiola Rosea is a powerful adaptogenic herb known for its myriad of health benefits, making it a highly sought-after ingredient in the world of nootropics. In this comprehensive guide, we’ll explore the numerous benefits of Rhodiola, its role in the groundbreaking nootropic supplement Iso Brain, and how it can help you achieve optimal cognitive performance.

What is Rhodiola Rosea?

Rhodiola Rosea, also known as golden root or Arctic root, is a plant native to the cold, mountainous regions of Europe, Asia, and Alaska. This adaptogenic herb has been used for centuries in traditional medicine to combat fatigue, enhance cognitive function, and improve physical performance.

As a key ingredient in Iso Brain, Rhodiola Rosea works synergistically with other nootropic ingredients like Acetyl L-Carnitine, Lion’s Mane, Cognizin, N-Acetyl L-Tyrosine, and Bacopa Monniera Extract to provide a comprehensive cognitive boost.

Rhodiola Benefits: A Deep Dive into the Science

Rhodiola’s nootropic benefits are backed by solid scientific research. Some of the most prominent benefits of Rhodiola include:

Enhanced Cognitive Function

Rhodiola is well-known for its ability to improve various aspects of cognitive function, such as memory, attention, and mental clarity. A study published in the journal Phytomedicine demonstrated that Rhodiola extract significantly improved cognitive performance in participants experiencing mental fatigue.

Reduced Mental Fatigue and Increased Energy

One of the primary benefits of Rhodiola is its ability to combat mental fatigue and increase energy levels. A double-blind, placebo-controlled study found that participants who received Rhodiola extract experienced a significant reduction in mental fatigue and an increase in overall well-being.

Mood Enhancement and Stress Reduction

As an adaptogen, Rhodiola helps the body better adapt to stress and promotes emotional well-being. Research published in the Nordic Journal of Psychiatry showed that Rhodiola Rosea effectively alleviated symptoms of mild to moderate depression and improved overall mood.

Boosted Physical Performance

In addition to its cognitive benefits, Rhodiola Rosea has also been shown to enhance physical performance. A study published in the International Journal of Sports Nutrition and Exercise Metabolism found that Rhodiola supplementation significantly increased endurance, strength, and overall physical performance.

Iso Brain: The Ultimate Nootropic Supplement

Iso Brain harnesses the power of Rhodiola Rosea and combines it with a potent blend of scientifically backed nootropic ingredients, including:

Together, these ingredients work synergistically to support optimal cognitive function, brain health, and overall well-being.

Clinical Research and Safety

Iso Brain is formulated with ingredients that have been extensively researched for their cognitive benefits. To learn more about the clinical research behind the ingredients in Iso Brain, visit the Clinical Research page on the Iso Brain website.

Iso Brain is safe to use as directed, providing you with a powerful cognitive boost without the need for a prescription or worry about adverse side effects.

Take Action and Experience the Benefits of Iso Brain

With its unique blend of scientifically proven ingredients, including Rhodiola Rosea, Iso Brain is the ultimate nootropic supplement for those looking to improve their cognitive performance, memory, focus, and overall brain health.

Don’t wait any longer to experience the incredible benefits of Iso Brain. Order Iso Brain now and unlock your full cognitive potential.

Remember to consult with a healthcare professional if you have any concerns or questions about incorporating Iso Brain into your daily routine.

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Nootropics Are Substances That Can Enhance Memory, Brain Health, Focus, Mood and Other Cognitive Processes, While Safely Supporting and Protecting Different Areas of the Brain. †

Rhodiola Rosea: A Closer Look at the Statistics and Medical Research

Rhodiola Rosea has been the subject of numerous scientific studies, highlighting its potential as a powerful adaptogen and natural cognitive enhancer. Let’s take a closer look at some of the key statistics and findings from the medical research on Rhodiola Rosea.

  1. Reduced Fatigue: A study published in the journal Phytomedicine found that Rhodiola Rosea supplementation significantly reduced mental fatigue and improved cognitive performance in a group of 56 young, healthy physicians working night shifts. After two weeks of supplementation, the physicians experienced a 20.5% improvement in mental fatigue scores, compared to the placebo group.

  2. Enhanced Cognitive Function: In a 12-week study with 120 participants, Rhodiola Rosea extract was found to improve cognitive function, specifically attention, by 11.6%. The study also reported a significant reduction in cortisol levels, suggesting that the herb may help the body better adapt to stress.

  3. Improved Exercise Performance: A double-blind, placebo-controlled study conducted on 24 healthy, active individuals demonstrated that acute Rhodiola Rosea supplementation could improve endurance exercise performance. Participants experienced a 3% increase in time to exhaustion during a standardized cycling test after taking Rhodiola Rosea.

  4. Mood Enhancement and Stress Reduction: A 6-week study involving 89 participants with mild-to-moderate depression found that Rhodiola Rosea supplementation resulted in significant improvements in overall depression, insomnia, and emotional instability scores. Participants experienced a 42% average improvement in depression scores, compared to the placebo group.

  5. Neuroprotection and Antioxidant Activity: A research article published in the Journal of Ethnopharmacology suggests that Rhodiola Rosea may offer neuroprotective benefits and potent antioxidant activity. The study found that the herb exhibited strong antioxidant effects, with its active components scavenging free radicals and protecting against oxidative stress-induced cell damage.

These statistics and research findings demonstrate the potential of Rhodiola Rosea as a natural nootropic and adaptogen, capable of supporting cognitive function, mood, and overall brain health. By incorporating Rhodiola Rosea into Iso Brain’s formula, you can experience these benefits alongside other powerful cognitive-enhancing ingredients.


Unlocking the Power of Iso Brain: Key Ingredients and Their Benefits

While Rhodiola Rosea is undoubtedly an essential component of Iso Brain, the supplement’s unique formula combines other potent ingredients that work synergistically to enhance cognitive function, promote brain health, and support overall well-being. Let’s explore some of these key ingredients and their benefits:

  1. Vitamin D3 (Cholecalciferol): Vitamin D3 plays a crucial role in maintaining bone health, immune function, and mental well-being. Research has shown that vitamin D deficiency can be linked to cognitive decline and mood disorders, making it a vital component for optimal brain health.

  2. Vitamin B3 (Niacin): Vitamin B3 is essential for converting food into energy, maintaining healthy skin, and supporting brain function. Niacin has been shown to protect brain cells from damage, promote healthy neurotransmitter function, and enhance cognitive performance.

  3. Vitamin B6 (P5P) (Pyridoxal 5 Phosphate): Vitamin B6 is involved in numerous metabolic processes, neurotransmitter synthesis, and hormone regulation. It has been linked to improved mood, cognitive function, and overall brain health.

  4. Vitamin B12 (Methylcobalamin): Vitamin B12 is crucial for maintaining healthy nerve cells, red blood cell production, and DNA synthesis. It has been associated with improved memory, mood, and cognitive performance.

  5. Acetyl L-Carnitine (ALCAR): Acetyl L-Carnitine is an amino acid that supports energy production in cells, promotes healthy brain function, and acts as a potent antioxidant. ALCAR has been shown to improve memory, learning, and overall cognitive performance.

  6. Lion’s Mane (Hericium Erinaceus): Lion’s Mane is a medicinal mushroom known for its neuroprotective and cognitive-enhancing properties. It has been shown to stimulate nerve growth factor (NGF) production, which is essential for the maintenance, growth, and survival of neurons.

  7. Cognizin® (Citicoline): Cognizin is a patented form of citicoline, a compound that supports brain cell function, promotes healthy neurotransmitter activity, and enhances cognitive performance. It has been shown to improve attention, memory, and overall cognitive function.

  8. N-Acetyl L-Tyrosine (NALT): N-Acetyl L-Tyrosine is an amino acid that plays a crucial role in the production of neurotransmitters like dopamine, norepinephrine, and epinephrine. It has been shown to support cognitive performance during periods of stress and fatigue.

  9. N-Acetyl Cysteine (NAC): NAC is an antioxidant that supports healthy liver function, detoxification, and glutathione production. It has been shown to protect brain cells from oxidative stress and support overall brain health.

  10. Bacopa Monnieri Extract (50% Bacosaponins): Bacopa Monnieri is a well-known Ayurvedic herb that has been used for centuries to improve cognitive function and memory. Studies have shown that it helps enhance learning, information retention, and overall cognitive performance.

  11. Turmeric Extract (95% Curcuminoids): Turmeric is a powerful anti-inflammatory and antioxidant spice. Its main active component, curcumin, has been shown to protect brain cells from damage, support healthy brain function, and improve mood and memory.

  12. Phosphatidylserine (From Sunflower): Phosphatidylserine is a phospholipid that supports healthy cell membrane function and communication between brain cells. It has been shown to improve cognitive function, memory, and focus.

  13. Dimethylaminoethanol (DMAE Bitartrate): DMAE is a compound that promotes the production of the neurotransmitter acetylcholine, which is essential for learning, memory, and cognitive function. Studies have shown that DMAE can improve focus, memory, and overall cognitive performance.

  14. Coenzyme Q10 (CoQ10): CoQ10 is a powerful antioxidant that supports cellular energy production and protects cells from oxidative damage. It has been shown to promote overall brain health and cognitive function.

These ingredients, combined with Rhodiola Rosea, create a powerful and effective nootropic supplement designed to help you reach your peak cognitive performance. Experience the difference Iso Brain can make in your life by visiting our shop and trying it for yourself. For more information on the clinical research behind Iso Brain’s ingredients, visit our clinical research page.

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Iso Brain: A Cost-Effective Solution for Optimal Brain Health

Purchasing high-quality nootropic ingredients individually can be expensive and time-consuming. Iso Brain offers a comprehensive, cost-effective solution by combining these powerful ingredients into one easy-to-take supplement. Let’s compare the costs of buying each ingredient separately IN BULK RAW POWDER to the cost of Iso Brain.

IngredientCost per Month
Vitamin D3 (Cholecalciferol)$7.00
Vitamin B3 (Niacin)$6.00
Vitamin B6 (P5P)$6.50
Vitamin B12 (MethylCobalamin)$8.00
Acetyl L-Carnitine (ALCAR)$14.00
Lion’s Mane (Hericium Erinaceus)$22.00
Cognizin® (Citicoline)$30.00
N-Acetyl L-Tyrosine (NALT)$12.00
Rhodiola Rosea Extract$18.00
N-Acetyl Cysteine (NAC)$9.00
Bacopa Monnieri Extract$20.00
Turmeric Extract$16.00
DMAE Bitartrate$10.00
Coenzyme Q10 (CoQ10)$15.00

A 30-day supply of Iso Brain, on the other hand, costs only $49.95. This represents a significant cost saving of $156.55 compared to purchasing each ingredient separately at $206.50.

By choosing Iso Brain, you’ll not only save money but also ensure that you’re getting a carefully formulated blend of ingredients designed to work synergistically for optimal brain health. Make the smart choice for your cognitive well-being and invest in Iso Brain today. Visit our shop to order now!


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"ISO brain 100% transparency promise"

We are transparent like our bottles, showing you an itemized breakdown of the exact amounts of our ingredients. You will not open a clear ISO BRAIN bottle to find it half full like a bag of chips and you will know exactly how much you are taking of each ingredient.

Supplement Facts

Serving Size 2 Capsules
Servings Per Container 30

† Percent Daily Value not established

Other Ingredients: Gelatin Capsule (Sodium Lauryl sulfate, Glycerin, Brilliant Blue FCF, FD & C Red No. 40, Titanium Dyoxide), Magnesium Stearate, Silicon Dioxide, Microcrystalline Cellulose, Maltrodextrin.

Coginizin® is a registered trademark of KYOWA HAKKO BIO CO, LTD.

NAC N-Acetyl- Cysteine

Top 10 Reasons to Buy Iso Brain Right Now

  1. Improve Memory and Recall: Iso Brain’s powerful blend of nootropic ingredients, including Rhodiola Rosea and Bacopa Monnieri, have been clinically proven to enhance memory and recall, giving you a competitive edge in your personal and professional life.

  2. Increase Focus and Concentration: Stay sharp and attentive throughout the day with Iso Brain’s potent formula, featuring ingredients such as Cognizin® (Citicoline) and N-Acetyl L-Tyrosine (NALT), which support mental clarity and sustained focus.

  3. Boost Cognitive Performance: Iso Brain’s unique combination of ingredients work synergistically to optimize brain function and enhance overall cognitive performance, helping you reach your full mental potential.

  4. Enhance Mental Energy and Alertness: Experience a boost in mental energy and alertness with Iso Brain’s natural ingredients, such as Acetyl L-Carnitine (ALCAR) and Coenzyme Q10 (CoQ10), which support cellular energy production and optimal brain function.

  5. Combat Stress and Fatigue: With adaptogenic herbs like Rhodiola Rosea and Ashwagandha, Iso Brain helps your body and mind adapt to stress, fight fatigue, and maintain peak performance under pressure.

  6. Promote a Positive Mood: Iso Brain’s mood-enhancing ingredients, such as Turmeric Extract and N-Acetyl Cysteine (NAC), have been shown to support a positive mood and overall emotional well-being.

  7. Protect Brain Health: Iso Brain’s antioxidant-rich formula, featuring ingredients like Vitamin D3 and Coenzyme Q10, helps protect brain cells from oxidative stress and supports overall brain health.

  8. Safe and Effective: Iso Brain is made with a carefully selected blend of natural, high-quality ingredients that have been extensively researched and proven to be safe and effective for daily use.

  9. Convenient and Easy to Use: Iso Brain’s easy-to-take capsules make it simple to incorporate into your daily routine, ensuring you get the cognitive support you need without any hassle.

  10. Backed by Clinical Research: Iso Brain’s ingredients are backed by extensive clinical research, so you can trust that you’re getting a top-notch nootropic supplement designed to deliver real results.

Don’t wait any longer to experience the benefits of Iso Brain for yourself. Visit our shop now to order Iso Brain and unlock your full cognitive potential!


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Made In The USA
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15 Premium Ingredients

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Vitamin B6 (P5P)

(Pyridoxal 5 Phosphate)5

Pyridoxal-5-Phosphate, or P5P as it is commonly known, is a more expensive and active form of vitamin B6. P5P is a required coenzyme for the biosynthesis of several neurotransmitters, including GABA, dopamine, norepinephrine, and serotonin. Some studies show P5P increasing mood, memory, performance and mental effort.†

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(ALCAR) 333mg

An amino acid that is naturally produced in the body which helps produce energy and can help increase energy production in the mitochondria. This acetylated version of carnitine is able to cross the blood-brain barrier. Its primary effect is on the production of acetylcholine which is one of the main neurotransmitters involved in memory, learning, computation, analysis and many other cognitive processes.†

LionsMane2 compact


(Hericium Erinaceus) 216mg

Hericium Erinaceus (also called Lion’s Mane) is an edible and medicinal mushroom. Lion’s Mane can induce Nerve Growth Factor synthesis in nerve cells which is essential for the maintenance of the basal forebrain cholinergic system. A double-blind placebo-controlled clinical trial study showed increased cognitive function scores for people who took Lion’s Mane vs a placebo group. †

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Bacopa Monniera Extract

(50% Bacosaponins)94mg

Created from the Brahmi plant which is native to the wetlands of India and has been a consistent part of traditional medicine for centuries. A 2013 study demonstrated that Bacopa Monniera extract has a potential to improve cognitive performance, particularly speed of attention by reducing choice reaction time.†

tumeric compact


(95% Curcuminoids) 87mg

Curcumin is a natural phenolic component of yellow curry spice, which is used in some cultures for the treatment of diseases associated with oxidative stress and inflammation. Recent studies show that curcumin also possesses neuroprotective and cognitive-enhancing properties.†

Phosphatidylserine 01 medium


(From Soy) 74mg

Phosphatidylserine is a phospholipid and is a component of the cell membrane. It plays a key role in cell cycle signaling, specifically in relationship to apoptosis. In a recent Japenese study, with oral administration of Soy-PS for 6 months improved memory function, especially delayed recall, in the elderly with memory complaints. †

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An amino acid considered a “building block” of protein. in some cases L-Tyrosine is also used to treat depression, anxiety, ADHD, cognitive disorders and treat chronic fatigue syndrome.†

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(5% Rosavins)106mg

Rhodiola rosea is a perennial flowering plant in the family Crassulaceae. In some clinical trials Rhodiola Rosea has been found to show anti fatiguing benefits for brain function.†

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N-acetyl cysteine (sometimes refered to as NAC) comes from the amino acid L-cysteine, that has been known as a strong antioxidant and one of the few supplements to help combat hangover symptoms from Alcohol.†

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(DMAE Bitartrate) 58mg

DMAE is a precursor to acetylcholine, which is one of the main memory-forming neurotransmitters in your brain. Higher acetylcholine levels have been linked with better performance on some memory tests.† As a nootropic, it is closely related to choline but due to a slightly different chemical structure it crosses the blood-brain barrier differently.†

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(Cholecalciferol) 400 IU

Vitamin D acts an immune system modulator and can be produced by the body using sunlight. present findings signify the crucial role of Vitamin D on the basic synaptic transmission and synaptic plasticity.† Due to weather changes, deficiency is common during the winter months. A recent study suggests that Vitamin D(3) supplementation during the winter may reduce the incidence of flu by 40%†

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(CoQ10) 50mg

COQ10: Co-Enzyme Q10 is a compound present in mitochondria of every cell in the body. the results show that lower COQ10 plays a role in the pathophysiology of depression and in particular in TRD and CFS accompanying depression.† COQ10 supplementation also has been known to promote slower brain deterioration, as seen in a study published in the 2002 “archives of neurology.” †

Cognizin 1



Cognizin®​ delivers a patented form of citicoline. Citicoline is a brain health ingredient that provides support for attention, focus and recall. Clinical studies have shown Cognizin to help improve attention, focus, motor speed and increase brain activity. †
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MethylCobalamin is more Bio-Available and expensive form of B12. The vitamin plays a key role in the normal functioning of the brain and nervous system.†

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(Niacin) 20mg

Also known as Niacin. this vitamin is known as a key Co-Enzyme in the production of cellular energy. Data from research suggests Vitamin B3 may be beneficial in preserving and enhancing neuroconitive function.†

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