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B3: Nootropic and Brain Supplement Facts for 2023


What is Vitamin B3?

Vitamin B3, also known as Niacin, is a crucial component of the Iso Brain formula. This essential nutrient plays a significant role in various processes within the body, including brain function, energy production, and DNA repair. In this article, we’ll explore the many benefits of Vitamin B3 for cognitive performance and overall brain health.

The Role of Vitamin B3 in Brain Function

Vitamin B3 is vital for optimal brain function as it is directly involved in the production of neurotransmitters, the chemical messengers that allow our neurons to communicate with one another. Specifically, Niacin contributes to the synthesis of acetylcholine, a neurotransmitter essential for learning, memory, and concentration. Learn more about the role of Vitamin B3 in brain function here.

How Vitamin B3 Benefits Cognitive Performance

1. Enhances Memory and Learning

Adequate levels of Vitamin B3 in the body are crucial for maintaining proper brain function. Research has shown that Niacin deficiency can lead to cognitive decline and memory impairment. Supplementing with Vitamin B3 has been shown to improve memory and learning capabilities, thanks to its role in neurotransmitter synthesis.

2. Boosts Energy Production

Vitamin B3 plays a significant role in energy production within our cells. It is a key component of the coenzymes NAD and NADP, which are responsible for converting the food we eat into usable energy. This process is vital for maintaining optimal brain function, as our brain requires a constant supply of energy to perform its tasks effectively. By supporting energy production, Niacin helps to maintain mental clarity and focus throughout the day.

3. Supports DNA Repair and Stress Response

Vitamin B3 is also involved in DNA repair and stress response within our cells. It helps to protect our brain cells from damage caused by oxidative stress and inflammation, both of which can contribute to cognitive decline and the development of neurodegenerative diseases. By supporting these protective processes, Niacin helps to maintain overall brain health and function.

Clinical Research on Vitamin B3 (Niacin) as a Nootropic

Vitamin B3, also known as Niacin, has been the subject of numerous clinical research studies exploring its potential as a nootropic. This essential vitamin plays a crucial role in various biochemical reactions in the brain, making it an essential component for optimal cognitive function.

  1. Boosting Brain Energy Metabolism

    A study published in the Journal of Clinical Biochemistry and Nutrition highlighted that Vitamin B3 is involved in the synthesis of NAD+ (nicotinamide adenine dinucleotide), a coenzyme essential for energy production in brain cells. By increasing the availability of NAD+, Niacin helps enhance cellular energy production, which can, in turn, support overall cognitive function.

  2. Protecting Against Neurodegeneration

    Research has shown that Vitamin B3 can help protect brain cells from damage caused by oxidative stress. A study published in the Journal of Neurochemistry demonstrated that Niacin helps mitigate the effects of oxidative stress by increasing the production of a protective enzyme called Sirtuin 1 (SIRT1). This enzyme plays a role in maintaining neuronal health and may help reduce the risk of neurodegenerative diseases.

  3. Supporting Memory and Learning

    Vitamin B3 has been found to contribute to improved memory and learning. A study published in the journal Neuroscience Letters found that Niacin supplementation led to an increase in spatial working memory in rats, suggesting its potential to positively influence memory and learning in humans as well.

  4. Promoting Brain Blood Flow

    Niacin is well-known for its vasodilating properties, which can help increase blood flow to the brain. Enhanced blood flow allows for better delivery of oxygen and nutrients to brain cells, supporting cognitive function. A review in the Journal of Clinical Lipidology highlights the importance of Niacin in maintaining healthy blood flow to the brain.

The clinical research on Vitamin B3 emphasizes its potential as a powerful nootropic, contributing to various aspects of cognitive health. By including Niacin in the Iso Brain formula, we strive to harness its numerous benefits for a comprehensive cognitive support supplement.

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Nootropics Are Substances That Can Enhance Memory, Brain Health, Focus, Mood and Other Cognitive Processes, While Safely Supporting and Protecting Different Areas of the Brain. †

Synergy with Other Iso Brain Ingredients

Vitamin B3 works in synergy with other essential nutrients found in Iso Brain to enhance cognitive performance. These include:

  • Vitamin D3 (Cholecalciferol): Vitamin D3 supports overall brain health by maintaining proper neurotransmitter balance and promoting the growth of new neurons.
  • Vitamin B6 (P5P) (Pyridoxal 5 Phosphate): Vitamin B6 is crucial for optimal brain function as it helps produce neurotransmitters and maintain healthy brain chemistry.
  • Vitamin B12 (MethylCobalamin): Vitamin B12 is essential for maintaining healthy nerve cells and supporting cognitive function, including memory and learning.

To explore other key ingredients in Iso Brain that work alongside Vitamin B3, check out our ingredient page.

The Importance of Vitamin B3 for Brain Health

Maintaining optimal levels of Vitamin B3 is essential for promoting brain health and cognitive performance. Iso Brain provides a potent blend of ingredients, including Niacin, to support your brain’s health and unlock its full potential. To learn more about the science behind Iso Brain and the clinical research supporting its ingredients, visit our clinical research page.

Boost Your Cognitive Performance with Iso Brain

Experience the benefits of Vitamin B3 and other powerful ingredients by incorporating Iso Brain into your daily routine. By providing the essential nutrients your brain needs to function at its best, Iso Brain can help improve memory, focus, and mental clarity. Don’t miss out on the opportunity to unlock your brain’s full potential.

How to Get Started with Iso Brain

Ready to experience the cognitive-enhancing effects of Vitamin B3 and Iso Brain’s other potent ingredients? Visit our shop page to purchase Iso Brain and start your journey towards improved brain health and performance today.

Stay Informed and Empowered

Knowledge is power, and staying informed about the latest research and developments in brain health and nootropics is essential for maintaining optimal cognitive performance. Iso Brain is committed to providing you with the most up-to-date information and resources to help you make informed decisions about your brain health. Be sure to explore our blog for more articles on various topics related to brain health, cognitive performance, and nootropics.

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Unlocking Your Brain’s Full Potential with Iso Brain

In today’s fast-paced world, it’s more important than ever to maintain optimal cognitive function. Iso Brain, a powerful nootropic supplement, is designed to help you achieve just that. By combining a carefully selected blend of ingredients, Iso Brain supports memory, brain health, clarity, and overall cognitive performance. Let’s dive into the benefits of each ingredient and see how they work together to unlock your brain’s full potential.

The Powerhouse Ingredients in Iso Brain

Iso Brain contains a potent mix of vitamins, amino acids, and natural extracts, all chosen for their nootropic benefits. These ingredients work synergistically to provide you with the best possible results. Here’s a closer look at each component:

  • Vitamin D3 (Cholecalciferol): Crucial for overall health, Vitamin D3 plays a role in brain development, memory, and mood regulation.
  • Vitamin B3 (Niacin): Niacin supports brain function, energy production, and DNA repair, contributing to optimal cognitive performance.
  • Vitamin B6 (P5P) (Pyridoxal 5 Phosphate): Vitamin B6 is essential for neurotransmitter synthesis, helping to improve memory and cognitive function.
  • Vitamin B12 (MethylCobalamin): Vitamin B12 plays a vital role in nerve health, mental clarity, and memory formation.

Amino Acids and Extracts for Enhanced Cognitive Performance

  • Acetyl L-Carnitine (ALCAR): ALCAR improves mitochondrial function, supports memory, and enhances overall brain health.
  • Lion’s Mane (Hericium Erinaceus): Lion’s Mane is a mushroom extract known for its neuroprotective properties, promoting nerve growth and cognitive function.
  • Cognizin® (Citicoline): Cognizin supports memory, focus, and overall brain health by increasing the production of neurotransmitters.
  • N-Acetyl L-Tyrosine (NALT): NALT is an amino acid that helps improve cognitive performance under stress, boosts mood, and supports mental clarity.
  • Rhodiola Rosea Extract (5% Rosavins): Rhodiola is an adaptogenic herb that enhances mental performance, reduces fatigue, and helps the body adapt to stress.
  • N-Acetyl Cysteine (NAC): NAC is a powerful antioxidant that supports brain health and detoxification.
  • Bacopa Monniera Extract (50% Bacosaponins): Bacopa is a natural nootropic that improves memory, focus, and overall cognitive function.
  • Tumeric Extract (95% Curcuminoids): Turmeric contains curcumin, which has potent anti-inflammatory and antioxidant properties, supporting brain health.
  • Phosphatidylserine (From Sunflower): [Phosphatatidylserine]( is a phospholipid that improves memory and cognitive function by supporting cell membrane integrity and communication between brain cells.
  • Dimethylaminoethanol (DMAE Bitartrate): DMAE boosts acetylcholine levels in the brain, enhancing memory, focus, and overall cognitive performance.
  • Coenzyme Q10 (CoQ10): CoQ10 is a powerful antioxidant that supports brain health and energy production.

The Science Behind Iso Brain

Numerous clinical studies support the efficacy of Iso Brain’s ingredients in improving cognitive performance. For an in-depth look at the research, head over to our clinical research page, where you’ll find comprehensive information on the science behind each ingredient.

The Power of Nootropics in Numbers

To truly appreciate the impact of nootropics on cognitive function, it’s essential to examine the research. A meta-analysis of 48 clinical trials revealed that several Iso Brain ingredients, such as Bacopa Monnieri, Citicoline, and Rhodiola Rosea, significantly improved cognitive performance compared to a placebo. Another study found that a combination of nootropics, including ALCAR, L-Tyrosine, and Phosphatidylserine, led to significant improvements in memory, attention, and executive functions.

Ensuring Iso Brain’s Safety and Efficacy

Iso Brain is designed to be safe and effective when used as directed. All ingredients have been carefully selected and tested for quality, ensuring that you receive the best possible nootropic experience.

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Exploring Other Key Ingredients in Iso Brain

Iso Brain’s unique formulation consists of several carefully selected ingredients that work synergistically to support optimal brain function. In addition to Vitamin B3, here’s a closer look at some of the other potent ingredients included in Iso Brain and their respective benefits:

  1. Vitamin D3 (Cholecalciferol): Essential for maintaining overall health, Vitamin D3 also plays a vital role in supporting cognitive function and mental well-being.

  2. Vitamin B6 (P5P) (Pyridoxal 5 Phosphate): A crucial component of neurotransmitter synthesis, Vitamin B6 contributes to improved mood, memory, and focus.

  3. Vitamin B12 (MethylCobalamin): This essential vitamin aids in maintaining the health of the nervous system and enhancing cognitive performance.

  4. Acetyl L-Carnitine (ALCAR): ALCAR is known for its neuroprotective properties and its ability to increase mental energy and cognitive function.

  5. Lion’s Mane (Hericium Erinaceus): This unique mushroom has demonstrated potential in supporting nerve growth, improving memory, and enhancing overall cognitive function.

  6. Cognizin® (Citicoline): A well-researched nootropic, Cognizin® helps support memory, focus, and overall cognitive health.

  7. N-Acetyl L-Tyrosine (NALT): NALT is a precursor to several vital neurotransmitters, improving mental performance, particularly under stress.

  8. Rhodiola Rosea Extract (5% Rosavins): An adaptogenic herb, Rhodiola Rosea is known for its ability to combat stress and fatigue while enhancing cognitive function.

  9. N-Acetyl Cysteine (NAC): NAC supports brain health by promoting antioxidant activity and protecting the brain from oxidative stress.

  10. Bacopa Monniera Extract (50% Bacosaponins): Bacopa has been traditionally used to improve memory, focus, and learning capabilities.

  11. Tumeric Extract (95% Curcuminoids): Curcumin, the active compound in turmeric, offers anti-inflammatory and antioxidant properties, promoting brain health.

  12. Phosphatidylserine (From Sunflower): Phosphatidylserine is an essential component of cell membranes, supporting memory and cognitive function.

  13. Dimethylaminoethanol (DMAE Bitartrate): DMAE is known for its ability to enhance focus, memory, and overall cognitive function.

  14. Coenzyme Q10 (CoQ10): CoQ10 is a powerful antioxidant that supports cellular energy production, which is crucial for maintaining optimal brain function.

    Each of these carefully chosen ingredients contributes to Iso Brain’s comprehensive formula, designed to target various aspects of cognitive health. The combined effects of these ingredients work together to provide an unparalleled nootropic experience.

    By incorporating Iso Brain into your daily routine, you can enjoy the numerous benefits that these powerful ingredients have to offer. With Iso Brain, you can expect enhanced memory, focus, clarity, and overall brain health, allowing you to perform at your best every day.

    Remember to check out our extensive clinical research page for more information on the scientific studies supporting the effectiveness of these ingredients.

    Now that you have a deeper understanding of Iso Brain’s unique formulation, why not give it a try and experience the cognitive benefits for yourself? Take the next step towards improved brain health by purchasing Iso Brain through our online store today.


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"ISO brain 100% transparency promise"

We are transparent like our bottles, showing you an itemized breakdown of the exact amounts of our ingredients. You will not open a clear ISO BRAIN bottle to find it half full like a bag of chips and you will know exactly how much you are taking of each ingredient.

Supplement Facts

Serving Size 2 Capsules
Servings Per Container 30

† Percent Daily Value not established

Other Ingredients: Gelatin Capsule (Sodium Lauryl sulfate, Glycerin, Brilliant Blue FCF, FD & C Red No. 40, Titanium Dyoxide), Magnesium Stearate, Silicon Dioxide, Microcrystalline Cellulose, Maltrodextrin.

Coginizin® is a registered trademark of KYOWA HAKKO BIO CO, LTD.

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Get B3 for Your Brain Health

Vitamin B3 (Niacin) is a critical nutrient for maintaining brain health and cognitive performance. Iso Brain’s unique blend of ingredients, including Vitamin B3, provides a comprehensive approach to support your brain’s health and unlock its full potential. Take charge of your cognitive well-being and invest in your brain’s future with Iso Brain. Order now on our shop page and experience the benefits for yourself.

The Bottom Line: Boost Your Brain Power with Iso Brain

If you’re looking to improve your memory, focus, and overall cognitive performance, Iso Brain is the perfect supplement to help you achieve your goals. With its potent blend of vitamins, amino acids, and natural extracts, Iso Brain is designed to unlock your brain’s full potential. Don’t let brain fog and fatigue hold you back any longer. Order Iso Brain today by visiting our shop and start experiencing the incredible benefits of this powerful nootropic.


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15 Premium Ingredients

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Vitamin B6 (P5P)

(Pyridoxal 5 Phosphate)5

Pyridoxal-5-Phosphate, or P5P as it is commonly known, is a more expensive and active form of vitamin B6. P5P is a required coenzyme for the biosynthesis of several neurotransmitters, including GABA, dopamine, norepinephrine, and serotonin. Some studies show P5P increasing mood, memory, performance and mental effort.†

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(ALCAR) 333mg

An amino acid that is naturally produced in the body which helps produce energy and can help increase energy production in the mitochondria. This acetylated version of carnitine is able to cross the blood-brain barrier. Its primary effect is on the production of acetylcholine which is one of the main neurotransmitters involved in memory, learning, computation, analysis and many other cognitive processes.†

LionsMane2 compact


(Hericium Erinaceus) 216mg

Hericium Erinaceus (also called Lion’s Mane) is an edible and medicinal mushroom. Lion’s Mane can induce Nerve Growth Factor synthesis in nerve cells which is essential for the maintenance of the basal forebrain cholinergic system. A double-blind placebo-controlled clinical trial study showed increased cognitive function scores for people who took Lion’s Mane vs a placebo group. †

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Bacopa Monniera Extract

(50% Bacosaponins)94mg

Created from the Brahmi plant which is native to the wetlands of India and has been a consistent part of traditional medicine for centuries. A 2013 study demonstrated that Bacopa Monniera extract has a potential to improve cognitive performance, particularly speed of attention by reducing choice reaction time.†

tumeric compact


(95% Curcuminoids) 87mg

Curcumin is a natural phenolic component of yellow curry spice, which is used in some cultures for the treatment of diseases associated with oxidative stress and inflammation. Recent studies show that curcumin also possesses neuroprotective and cognitive-enhancing properties.†

Phosphatidylserine 01 medium


(From Soy) 74mg

Phosphatidylserine is a phospholipid and is a component of the cell membrane. It plays a key role in cell cycle signaling, specifically in relationship to apoptosis. In a recent Japenese study, with oral administration of Soy-PS for 6 months improved memory function, especially delayed recall, in the elderly with memory complaints. †

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An amino acid considered a “building block” of protein. in some cases L-Tyrosine is also used to treat depression, anxiety, ADHD, cognitive disorders and treat chronic fatigue syndrome.†

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(5% Rosavins)106mg

Rhodiola rosea is a perennial flowering plant in the family Crassulaceae. In some clinical trials Rhodiola Rosea has been found to show anti fatiguing benefits for brain function.†

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N-acetyl cysteine (sometimes refered to as NAC) comes from the amino acid L-cysteine, that has been known as a strong antioxidant and one of the few supplements to help combat hangover symptoms from Alcohol.†

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(DMAE Bitartrate) 58mg

DMAE is a precursor to acetylcholine, which is one of the main memory-forming neurotransmitters in your brain. Higher acetylcholine levels have been linked with better performance on some memory tests.† As a nootropic, it is closely related to choline but due to a slightly different chemical structure it crosses the blood-brain barrier differently.†

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(Cholecalciferol) 400 IU

Vitamin D acts an immune system modulator and can be produced by the body using sunlight. present findings signify the crucial role of Vitamin D on the basic synaptic transmission and synaptic plasticity.† Due to weather changes, deficiency is common during the winter months. A recent study suggests that Vitamin D(3) supplementation during the winter may reduce the incidence of flu by 40%†

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(CoQ10) 50mg

COQ10: Co-Enzyme Q10 is a compound present in mitochondria of every cell in the body. the results show that lower COQ10 plays a role in the pathophysiology of depression and in particular in TRD and CFS accompanying depression.† COQ10 supplementation also has been known to promote slower brain deterioration, as seen in a study published in the 2002 “archives of neurology.” †

Cognizin 1



Cognizin®​ delivers a patented form of citicoline. Citicoline is a brain health ingredient that provides support for attention, focus and recall. Clinical studies have shown Cognizin to help improve attention, focus, motor speed and increase brain activity. †
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MethylCobalamin is more Bio-Available and expensive form of B12. The vitamin plays a key role in the normal functioning of the brain and nervous system.†

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(Niacin) 20mg

Also known as Niacin. this vitamin is known as a key Co-Enzyme in the production of cellular energy. Data from research suggests Vitamin B3 may be beneficial in preserving and enhancing neuroconitive function.†

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